Table 1 Brain metabolite concentration and acquisition time of various MRSI techniques

3D PRESS-MRSI

144/1100

NAA: 10.1 ± 0.64

21.12

Centre of brain/ 12 × 12 × 8 cm³/1 cm³/3 T

[40]

3D PRESS-MRSI

144/1100

NAA: 6.9 ± 1.3, Cho: 6.5 ± 1.4 Cr: 6.1 ± 1.2

17

Not reported/ 12x12x8 and 16x16x8 cm³/1 cm³/3 T

[36]

3D PRESS-MRSI

144/1100

Cho/NAA:(0.51–0.54)

21.12

Not reported/ 12 × 12 × 8 cm³/ 1 cm³/3 T

[46]

Multiple 2D-MRSI

144/ 2300

NAA:2.5 ± 4.47, Cho:2.94 ± 9.71, Cr:7.3 ± 4.09

26

Whole brain scans/ Not reported

[95]

2D-MRSI

135/1500

MS patients: NAA:9.48 ± 0.73

Controls: NAA:11.58 ± 0.37

NR^b

WM and GM/ 16 × 16 cm²/ 2 cm³/1.5 T

[112]

3D PRESS-MRSI with OVS

144/1500

Cho/Cr :1.24

NAA/Cr:1.94

9

Whole brain/ 16 × 16 × 16, 18x18x16 cm³/1 cm³/3 T

[37]