Selective activation of miRNAs of the primate-specific chromosome 19 miRNA cluster (C19MC) in cancer and stem cells and possible contribution to regulation of apoptosis

Table 2 Expression of C19MC miRNAs in different stem cell types

Stem cell type	Potency	miRNA^a		No.
Stem cell type	Potency	AAGUGC seed sequence^b	Others	No.
iPSC/hESC	Pluripotent	16 miRNAs	29 miRNAs	45
MSC	Multipotent
One cell line		miR-519d-3p, miR-526b-3p	miR-512-5p, miR-516a-3p, miR-517a-5p, miR-517b-3p, miR-518f-5p, miR-518f-3p	8
Both cell lines		miR-512-3p, miR-519b-3p, miR-520a-3p, miR-520d-3p, miR-520g-3p, miR520h	miR-498, miR-518a-3p, miR-518b, miR-518e-5p, miR-518e-3p, miR-521, miR-526a, miR-526b-5p	14
HWP	Unipotent	miR-520a-3p, miR-520g-3p, miR-512-3p	miR-498, miR-518a-3p, miR-518b, miR-518e-3p, miR-521	8
All cell lines	Pluri-/multi-/unipotent	miR-520a-3p, miR-520g-3p	miR-498, miR-512-3p, miR-518a-3p, miR-518b, miR-518e-3p, miR-521	8

^amiRNAs in bold letters were used for further quantification as depicted in Fig. 1. ^bAAGUGC seed sequence-containing miRNAs are taken from Fig. 2

ISSN: 1423-0127