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Table 1 Advantages and disadvantages of therapeutic peptides (Adopted from [25])

From: Evaluation of the use of therapeutic peptides for cancer treatment

Advantages

Disadvantages

High potency of action

Metabolic instability

High target specificity and selectivity

Poor membrane permeability

Wide range of targets

Poor oral bioavailability

Low toxicity

Poor solubility

Fewer side effects

Rapid clearance

Low accumulation in tissues

High manufacturing cost

High biological and chemical diversity

Poor activity