From: Evaluation of the use of therapeutic peptides for cancer treatment
Advantages | Disadvantages |
---|---|
High potency of action | Metabolic instability |
High target specificity and selectivity | Poor membrane permeability |
Wide range of targets | Poor oral bioavailability |
Low toxicity | Poor solubility |
Fewer side effects | Rapid clearance |
Low accumulation in tissues | High manufacturing cost |
High biological and chemical diversity | Poor activity |