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Table 1 Advantages and disadvantages of therapeutic peptides (Adopted from [25])

From: Evaluation of the use of therapeutic peptides for cancer treatment

Advantages Disadvantages
High potency of action Metabolic instability
High target specificity and selectivity Poor membrane permeability
Wide range of targets Poor oral bioavailability
Low toxicity Poor solubility
Fewer side effects Rapid clearance
Low accumulation in tissues High manufacturing cost
High biological and chemical diversity Poor activity