Associations of estradiol levels and genetic polymorphisms of inflammatory genes with the risk of ischemic stroke

Table 3 Association between the polygenic risk score and the risk of ischemic stroke

Polygenic risk score quartiles	Total
	Cases/Controls	OR^a (95% CI)	P-value
1st	254/300	1.0
2nd	112/114	1.12(0.75–1.65)	0.5801
3rd	74/77	1.17(0.75–1.84)	0.5029
4th	184/133	1.57(1.12–2.19)	0.0084
		p for trend	0.0050

^aAdjusted for age, body mass index, cigarette smoking/alcohol consumption, hypertension, diabetes mellitus, heart disease, and stroke family history

ISSN: 1423-0127