Fig. 4
Lineweaver-Burk plots for [14C]L-citrulline uptake by TR-BBB cells showing competitive inhibition by L-dopa and gabapentin. [14C]L-citrulline (44.4 μM) uptake was performed in the presence of 300 μM L-dopa (close circle) and 300 μM gabapentin (close triangle) or in their absence (open circle) in TR-BBB cells at pH 7.4 and 37 °C for 5 min. The data represents the mean ± S.E.M. (n = 3–4)