Fig. 6
Effect of LAT1, system b0,+ and CAT1 siRNA on the expression of each mRNA (a) and [14C]L-citrulline uptake (b) in TR-BBB cells. a The transcript levels of LAT1, system b0,+ and CAT1 were determined by quantitative real-time PCR analysis and normalized to those of GAPDH. b [14C]L-citrulline (44.4 μM) uptake was performed at 37 °C for 5 min. Each column represents the mean ± S.E.M. (n = 3–4). **p < 0.01, ***p < 0.001; significantly different from control