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Fig. 5 | Journal of Biomedical Science

Fig. 5

From: Aldehyde dehydrogenase 2*2 knock-in mice show increased reactive oxygen species production in response to cisplatin treatment

Fig. 5

ALDH2*2 knock-in mice show higher levels of ROS with cisplatin treatment in the cytosolic fraction of lung and brain. ALDH2*2 knock-in mice were treated with cisplatin, euthanized in two days and tissues were collected. Cell homogenates were spun to isolate supernatant, which includes cytosolic fraction from lungs and brains (a and b) and ROS level was measured. Results represent mean ± SEMs (*p < 0.05 vs. PBS HET control (t-test))

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Journal of Biomedical Science

ISSN: 1423-0127