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Table 1 Results of animal behavior, neuronal tracing of WGA-HRP and 5-TH immunoreactivity at 12 weeks after injury and treatment

From: Improving the regenerative potential of olfactory ensheathing cells by overexpressing prostacyclin synthetase and its application in spinal cord repair

Rats WGA-HRP tracing 5-HT Behavioral test (12 W)
Anterograde Retrograde   BBB CBS
Tx only
 1 -   - 0 80
 2   - - 0 80.5
 3 -   - 0.5 77.5
 4    - 0.5 76
  0% 0%   
Tx + OEC Tp
 5 -   - 5 63
 6   - - 2.5 65
 7 -   - 4.5 60
 8    + 3 64.5
 9 -   - 2 64.5
 10 -   - 3.5 63
  0% 16.7%   
Tx + AdPGIS-OEC Tp
 11 + (T12)   + 7 44
 12 -   + 6 46.5
 13 -   - 4 59
 14 + (T12)   + 6 46
 15   - - 3 66
  40% 60%   
  1. A few 5HT (+) fibers were found in the distal stump, within 1 mm distal to the transected gap, in one Tx + OEC Tp and three Tx + AdPGIS-OEC Tp rats
  2. Anterograde tracing was conducted from motor cortex in experimental rats. WGA (+) fibers were found in the thoracic level 12 in two Tx + AdPGIS-OEC Tp rats. Whereas retrograde tracing was conducted from T12, no WGA (+) signals were found in the motor cortex of SCI rats (one rat per group)