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Fig. 3 | Journal of Biomedical Science

Fig. 3

From: New insights into Blimp-1 in T lymphocytes: a divergent regulator of cell destiny and effector function

Fig. 3

Overview of Blimp-1-mediated regulations in T cells. a Broad influence of Blimp-1 in the expression of different molecules. Bcl-6, B cell lymphoma-6; Blimp-1, B lymphocyte-induced maturation protein-1; Id3, Inhibitor of DNA binding 3; IFN-γ, interferon-γ; IL, Interleukin; IL2ra, Interleukin 2 receptor subunit alpha; PD-1, Programmed death-1. The solid line indicates direct action. The dashed line indicates regulations that require further investigation for underlying mechanisms. b Blimp-1 regulates divergent functions of T cells. +: Positive regulation; −: Negative regulation; x: Unidentified regulation

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