Skip to main content

Table 2 Virulence of the lrp mutants in the mouse

From: Lrp, a global regulator, regulates the virulence of Vibrio vulnificus

Strain

Description

LD50 (cfu/mouse)

Fold relative to YJ016

YJ016

Wild type

4.84 × 105

1

NY303

Spontaneous attenuated mutant

1.99 × 108

411

YH01

YJ016Δlrp

1.45 × 108

300

YH03

YH01(plrp)

3.72 × 105

0.77

YH06

YJ016 lrp*

5.46 × 106

11

NY303–2

YJ016 ΔvvhΔvpl

9.49 × 105

2

CH08

NY303–2 -lrp*

7.00 × 107

145

CS9133

Wild-type strain (biotype 1)

3.79 × 105

0.78

CH09

CS9133Δlrp

4.43 × 107

92

CECT4999

Wild-type strain (biotype 2)

2.50 × 105

0.52

CH10

CECT4999Δlrp

6.32 × 107

131

  1. The bacteria were injected subcutaneously into the mouse, and the mortality was recorded within 72 h