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Table 1 Open field behavioral analysis of line Kctd1 I27N

From: Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1 I27N mutant mice

Parameter Heterozygous mutant males Wild-type males Heterozygous mutant females Wild-type females Genotype: P-value
Distance traveled – total (cm) 8834 ± 2939 10,050 ± 2329 9823 ± 2178 10,138 ± 2682  
Number of rearings - total 46 ± 41 75 ± 42 56 ± 45 74 ± 44 0.04
Percent distance in the center – total 10.4 ± 8.5 13.1 ± 7.3 12.5 ± 9.3 14.7 ± 8.3  
Percent time spent in the center - total 6.9 ± 6.1 9.0 ± 5.6 8.8 ± 7.9 10.2 ± 6.5
Whole arena - resting time (sec) 47 ± 38 79 ± 36 70 ± 57 95 ± 58 0.03
Whole arena - average speed (cm/s) 7.7 ± 2.7 9.0 ± 2.3 8.8 ± 2.2 9.3 ± 2.8  
Latency to enter in the center (sec) 349 ± 377 125 ± 209 122 ± 228 81 ± 137 0.047
Number of entries in the center 59 ± 51 76 ± 45 77 ± 57 87 ± 54  
  1. 9-week-old mice were tested in the open field for 20 min. Number per genotype and sex: n = 15. Data are presented as mean ± standard deviation. Significance vs. wild-type controls: Exact P values are indicated for P < 0.05