Table 1 Open field behavioral analysis of line Kctd1 I27N
Parameter | Heterozygous mutant males | Wild-type males | Heterozygous mutant females | Wild-type females | Genotype: P-value |
|---|---|---|---|---|---|
Distance traveled – total (cm) | 8834 ± 2939 | 10,050 ± 2329 | 9823 ± 2178 | 10,138 ± 2682 | |
Number of rearings - total | 46 ± 41 | 75 ± 42 | 56 ± 45 | 74 ± 44 | 0.04 |
Percent distance in the center – total | 10.4 ± 8.5 | 13.1 ± 7.3 | 12.5 ± 9.3 | 14.7 ± 8.3 | |
Percent time spent in the center - total | 6.9 ± 6.1 | 9.0 ± 5.6 | 8.8 ± 7.9 | 10.2 ± 6.5 | |
Whole arena - resting time (sec) | 47 ± 38 | 79 ± 36 | 70 ± 57 | 95 ± 58 | 0.03 |
Whole arena - average speed (cm/s) | 7.7 ± 2.7 | 9.0 ± 2.3 | 8.8 ± 2.2 | 9.3 ± 2.8 | |
Latency to enter in the center (sec) | 349 ± 377 | 125 ± 209 | 122 ± 228 | 81 ± 137 | 0.047 |
Number of entries in the center | 59 ± 51 | 76 ± 45 | 77 ± 57 | 87 ± 54 |