Table 5 Hematological analysis of line Kctd1 I27N
Parameter | Heterozygous mutant males | Wild-type males | Heterozygous mutant females | Wild-type males | Genotype: P-value |
|---|---|---|---|---|---|
WBC (103/μl) | 10.6 ± 1.5 | 10.6 ± 2.0 | 10.9 ± 1.8 | 9.6 ± 1.2 | |
RBC (106/μl) | 9.5 ± 0.4 | 10.2 ± 0.3 | 9.8 ± 0.4 | 9.8 ± 0.3 | 0.001 |
PLT (103/μl) | 989 ± 158 | 1051 ± 72 | 982 ± 63 | 1002 ± 60 | |
HGB (g/dl) | 15.4 ± 0.6 | 16.5 ± 0.5 | 15.7 ± 0.6 | 16.3 ± 0.8 | < 0.001 |
HCT (%) | 44.8 ± 1.7 | 48.1 ± 1.3 | 46.0 ± 1.7 | 46.6 ± 1.3 | < 0.001 |
MCV (fl) | 47.1 ± 0.6 | 47.3 ± 0.5 | 47.1 ± 0.5 | 47.6 ± 0.6 | 0.005 |
MCH (pg) | 16.1 ± 0.5 | 16.2 ± 0.3 | 16.1 ± 0.3 | 16.6 ± 0.5 | 0.005 |
MCHC (g/dl) | 34.3 ± 1.0 | 34.2 ± 0.5 | 34.3 ± 0.7 | 34.9 ± 1.0 |