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Table 3 Effect of NOS inhibitors on NOS and SOD activity in young and adult Wistar rats

From: Age-dependent redox status in the brain stem of NO-deficient hypertensive rats

Activity

Young rats

Adult rats

Control

7-NI

L-NAME

Control

7-NI

L-NAME

NOS (pkat/g proteins)

95,8 ± 76,45

117,4 ± 90,6

-12,1 ± 21,6*#

14,9 ± 6,7

16,2 ± 6

1 ± 1*#

SOD (U/mg proteins)

1,58 ± 0,5

3,04 ± 0,8*#

1,57 ± 0,5

4,96 ± 0,7

5,98 ± 0,8

6,18 ± 1

  1. Activity of SOD were expressed as U/mg of proteins and activity of NOS as pkat/g of proteins. Data represent mean ± std. dev., *P < 0.05, L-NAME vs. control; # P < 0.05, L-NAME vs. 7-NI.7-NI (7-nitroindazole), L-NAME (NG-nitro-L-arginine methyl esther), NOS (nitric oxide synthase), SOD (superoxide dismutase)
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Journal of Biomedical Science

ISSN: 1423-0127