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Table 3 Effect of NOS inhibitors on NOS and SOD activity in young and adult Wistar rats

From: Age-dependent redox status in the brain stem of NO-deficient hypertensive rats

Activity Young rats Adult rats
Control 7-NI L-NAME Control 7-NI L-NAME
NOS (pkat/g proteins) 95,8 ± 76,45 117,4 ± 90,6 -12,1 ± 21,6*# 14,9 ± 6,7 16,2 ± 6 1 ± 1*#
SOD (U/mg proteins) 1,58 ± 0,5 3,04 ± 0,8*# 1,57 ± 0,5 4,96 ± 0,7 5,98 ± 0,8 6,18 ± 1
  1. Activity of SOD were expressed as U/mg of proteins and activity of NOS as pkat/g of proteins. Data represent mean ± std. dev., *P < 0.05, L-NAME vs. control; # P < 0.05, L-NAME vs. 7-NI.7-NI (7-nitroindazole), L-NAME (NG-nitro-L-arginine methyl esther), NOS (nitric oxide synthase), SOD (superoxide dismutase)