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Fig. 4 | Journal of Biomedical Science

Fig. 4

From: Comprehensive comparison of three different animal models for systemic inflammation

Fig. 4

Immunohistochemical evaluation of iNOS expression. At the time point indicated, mice were sacrificed and the livers were collected for immunohistochemical analysis of iNOS expression (red-brown color, counterstaining with hematoxylin). Representative photomicrographs from one of 4–6 different tissue samples each are shown (original magnification: (a, b) 400×, arrows are used to exemplarily show iNOS expressing infiltrating neutrophil granulocytes). The time points 0 h, 4 h, 12 h, 24 h and 72 h were chosen as representative time points to show the course. The staining results after PCI treatment are not depicted separately but can be found in the additional file 3 as the course was very similar to that observed after LPS administration, with the only difference, however, that less iNOS positive cells are to be seen

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