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Fig. 3 | Journal of Biomedical Science

Fig. 3

From: Rosmarinic acid induces rabbit articular chondrocyte differentiation by decreases matrix metalloproteinase-13 and inflammation by upregulating cyclooxygenase-2 expression

Fig. 3

Ros. A reduces MMP-13 expression in rabbit articular chondrocytes. Rabbit primary cultured articular chondrocytes were treated with the indicated concentrations of rosmarinic acid (Ros. A) for 24 h or 75 μg/mL Ros. A for the indicated time periods. a and b Expression of MMP-13 and actin was detected by western blot analysis. Actin was used as the loading control (upper panel). The relative amounts of MMP-13 were quantified by densitometry measurements (Image J) (lower panel). The results represent three independent experiments. Values shown are the means ± SD; *p < 0.05 vs. control cells

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