Male non-insulin users with type 2 diabetes mellitus are predisposed to gastric corpus-predominant inflammation after H. pylori infection

Table 1 Comparison of gastric histology assessed according to Updated Sydney System scores among patients with diabetes and non-diabetes controls stratified by gender

Characters/mean(SD) or %(n)		DM (n = 129)			Non-DM (n = 129)			P value DM vs. non-DM
Characters/mean(SD) or %(n)		Male (n = 73)	Female (n = 56)	P value male vs. female	Male (n = 73)	Female (n = 56)	P value male vs. female	P value DM vs. non-DM
Age (years)		59.2 (11.0)	61.0 (10.2)	0.35	59.4 (11.2)	60.8 (10.3)	0.46	–
Non-ulcers gastritis^a		53.4 (39)	62.5 (35)	0.30	26.0 (19)	69.6 (39)	< 0.001	0.046
CIS^c	Antrum^b	2.85 (0.49)	2.95 (0.30)	0.18	2.81 (0.57)	2.77 (0.60)	0.60	0.13
	Body^a	2.68 (0.62)	2.66 (0.72)	0.79	2.32 (0.85)	2.70 (0.57)	0.01	0.02
	Cardia	2.40 (0.81)	2.30 (0.87)	0.58	2.12 (0.91)	2.46 (0.79)	0.03	0.45
AIS^c	Antrum	1.84 (0.62)	2.02 (0.40)	0.08	1.71 (0.81)	1.77 (0.85)	0.58	0.13
	Body^a	1.40 (0.95)	1.54 (0.89)	0.42	1.05 (1.03)	1.39 (0.95)	0.06	0.04
	Cardia	1.16 (1.00)	0.86 (1.02)	0.09	0.90 (1.00)	1.16 (0.99	0.15	0.90
LF^c	Antrum	2.15 (2.11)	2.32 (2.01)	0.52	1.64 (1.87)	1.84 (1.87)	0.55	0.04
	Body^a	1.49 (1.81)	1.29 (1.72)	0.48	0.66 (1.11)	0.70 (1.04)	0.70	0.001
	Cardia	0.85 (1.53)	0.48 (0.89)	0.18	0.53 (0.96	0.48 (0.76)	0.96	0.74
HPD^c	Antrum	3.36 (1.31)	3.39 (1.30)	0.92	3.29 (1.64)	3.23 (1.41)	0.60	0.94
	Body	3.21 (1.24)	3.36 (1.18)	0.42	3.16 (1.38)	3.41 (1.32)	0.32	0.77
	Cardia	2.75 (1.38)	2.63 (1.27)	0.61	2.77 (1.51)	2.98 (1.42	0.46	0.24
IM	Antrum	30.1 (22)	26.8 (15)	0.68	38.4 (28)	33.9 (18)	0.46	0.23
	Body	15.1 (11)	17.9 (10)	0.67	15.1 (11)	10.7 (6)	0.47	0.48
	Cardia	1.4 (1)	3.6 (2)	0.58	0	1.8 (1)	0.43	0.31
AT	Antrum	67.1 (49)	67.9 (38)	0.93	68.5 (50)	62.5 (35)	0.48	0.79
	Body	34.2 (25)	23.2 (13)	0.17	21.9 (16)	28.6 (16)	0.39	0.40
	Cardia	17.8 (13)	14.3 (8)	0.62	12.3 (9)	8.9 (5)	0.54	0.19

SD standard deviation, CIS chronic inflammation score, AIS acute inflammation score
LF lymphoid follicle, HPD H. pylori density, IM intestinal metaplasia, AT atrophy
DM Patients with diabetes, Non-DM patients without diabetes (controls)
^a: p < 0.05, male patients with and without DM
^b: p < 0.05, female patients with and without DM
^c: Mann-Whitney U test

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