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Fig. 2 | Journal of Biomedical Science

Fig. 2

From: Atrial ERK1/2 activation in the embryo leads to incomplete Septal closure: a novel mouse model of atrial Septal defect

Fig. 2

TAMEK/MH DTg mice developed ASD. a Heart from DOX-free DTg with enlarged right atrium compared to WT. b Anatomical dissection showed an unfused open foramen ovale (dashed circle) in the atrial septal wall of DTg hearts. c Comparison of progeny of 4 genotypes at 14-days of age reveals enlarged hearts (and in particular, enlarged right atria), growth retardation, and atrial septal defects in DTg’s. The distribution of progeny followed Mendel’s Law of segregation at birth

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Journal of Biomedical Science

ISSN: 1423-0127