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Table 1 Clinical Characteristics in Brugada Syndrome Patients With or Without the G Allele of rs1805124 (H558R+ Group or H558R- Group)

From: H558R, a common SCN5A polymorphism, modifies the clinical phenotype of Brugada syndrome by modulating DNA methylation of SCN5A promoters

  H558R- group (N = 91) H558R+ group (N = 9) P value
Age (years) 44 ± 14 53 ± 12 0.10
Sex (male%) 90.1% 100% 0.20
History of VF 29.7% 0% 0.01
History of syncope 25.3% 0% 0.02
Family history of SCD 35.1% 22.2% 0.43
Atrial Fibrillation 15.4% 33.3% 0.21
Induction of VF 51.6% 77.7% 0.30
  1. VF ventricular fibrillation, SCD sudden cardiac death