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Table 1 Clinical Characteristics in Brugada Syndrome Patients With or Without the G Allele of rs1805124 (H558R+ Group or H558R- Group)

From: H558R, a common SCN5A polymorphism, modifies the clinical phenotype of Brugada syndrome by modulating DNA methylation of SCN5A promoters

 

H558R- group (N = 91)

H558R+ group (N = 9)

P value

Age (years)

44 ± 14

53 ± 12

0.10

Sex (male%)

90.1%

100%

0.20

History of VF

29.7%

0%

0.01

History of syncope

25.3%

0%

0.02

Family history of SCD

35.1%

22.2%

0.43

Atrial Fibrillation

15.4%

33.3%

0.21

Induction of VF

51.6%

77.7%

0.30

  1. VF ventricular fibrillation, SCD sudden cardiac death
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Journal of Biomedical Science

ISSN: 1423-0127