Fig. 4From: MicroRNA-365 alleviates morphine analgesic tolerance via the inactivation of the ERK/CREB signaling pathway by negatively targeting β-arrestin2Protein expressions of β-arrestin2, ERK, p-ERK, CREB and p-CREB of rats in spinal cord tissues in each group after administration at day 7. Note: A, western blotting image of β-arrestin2, ERK, p-ERK, CREB and p-CREB; B, relative expressions of β-arrestin2, ERK, p-ERK, CREB and p-CREB; N = 8; *, P < 0.05 compared with the control group; #, P < 0.05 compared with the morphine tolerance group; ERK, extracellular signal-regulated kinase; CREB, cAMP-response element binding protein; NC, negative controlBack to article page