Fig. 3

Effect of VIP plasmid on protein expressions of biomarkers in synoviocytes. TNF-α and IL-2 expressions (a). Collagen II and OPG expressions (b). MMP-13 and ADAMTS-5 expressions (c). Compared with Sham+NC plasmid group, **P < 0.01, Compared with OA + NC plasmid group, ##P < 0.01