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Fig. 3 | Journal of Biomedical Science

Fig. 3

From: Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity

Fig. 3

Effects of danthron structural analogs on interaction of HO isozyme with CPR. a The structures of danthron analogs. b Non-linear regression curves showing the effects of dantron and structural analogs on HO-1/CPR or HO-2/CPR interaction. Data show the mean ± SE of four independent experiments. c HEK293T cells were treated with 20 μM of indicated compounds for 16 h. Cell lysates were then prepared and the expression levels of endogenous CPR and HO-1 were examined by Western blot analysis

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Journal of Biomedical Science

ISSN: 1423-0127