Fig. 6

Danthron attenuates HO-1-induced cancer cell migration. a and b Wounds were made in confluent mock or HO-1 over-expressing HeLa cells and the cell migration toward wound area in the absence or presence of indicated concentration of danthron was examined at 24 h. Each treatment was performed in triplicate. The representative images are shown in a. The wound healing area of each treated group was quantified and shown in b. Data are the mean ± SE of three independent experiments. c and d Wound healing assays were performed in mock or HO-1 over-expressing HeLa cells in the absence or presence of 20 μM of indicated compounds as described above. The representative images are shown in c. The wound healing area of each treated group was quantified and shown in d. Data shown are the mean ± SE of three independent experiments