Fig. 1From: Unique depot formed by an oil based vaccine facilitates active antigen uptake and provides effective tumour controlGraphs demonstrating volumetric changes in inguinal lymph nodes and tumours over the course of the study comparing DPX-R9F(n = 23) and w/o-R9F (n = 29) and Histological Evaluation of Site of Injection for DPX-R9F and w/o-R9F. a Tumour volume time course (mm3). b) Normalized % amount of SPIO-R9F remaining at the SOI. c % Right lymph node (RLN) volume increase over time (draining vaccine site). d Ratio of RLN volume over LLN volume. Data on graphs is mean ± SE. Significance was calculated using a 2-way ANOVA to compare overall differences across groups and time, and Holm-Sidak corrected t-tests to compare individual time points, * = p < 0.1, ** = p < 0.05. SOIs were extracted from 5 mice per group 14 days after immunization, sectioned and stained by H&E. Representative figures for 2 different mice are shown for DPX-R9F (e, g) and w/o-R9F (f, h)Back to article page