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Table 2 Antibiotic susceptibility profiles of S. pneumoniae isolates

From: Comparative genomic analysis of ten clinical Streptococcus pneumoniae collected from a Malaysian hospital reveal 31 new unique drug-resistant SNPs using whole genome sequencing

Isolate a

MIC (μg/ml)b

PEN c

CTX c

ERY c

TET c

SPS1

2

1

2

16

SPS2

2

1

> 2

> 16

SPS3

4

1

> 2

> 16

SPS4

0.06

≤0.063

≤0.016

> 16

SPS5

1

0.125

0.031

4

SPS6

0.06

≤0.063

≤0.016

≤0.125

SPS7

2

2

> 2

> 16

SPS8

0.5

> 8

2

> 16

SPS9

0.25

8

2

16

SPS10

2

2

> 2

16

  1. aIsolates SPS1, SPS2, and SPS3 are non-susceptible to all antibiotics. Isolate SPS4 is susceptible to penicillin, cefotaxime, and erythromycin, but resistant to tetracycline. SPS5 is susceptible to cefotaxime and erythromycin, but resistant to penicillin and tetracycline. SPS6 is susceptible to all four antibiotics. SPS7 and SPS10 are resistant to all four antibiotics, SPS8 and SPS9 were resistant to all antibiotics except penicillin
  2. bMIC Minimum inhibitory concentration
  3. cPEN Penicillin, CTX Cefotaxime, ERY Erythromycin, TET Tetracycline