From: Regenerative abilities of mesenchymal stem cells through mitochondrial transfer
S. No | MSCs Type | Recipient Cell | Mode of Transfer | Action | References |
---|---|---|---|---|---|
1 | BM-MSCs | A549 Cell Line | Cellular Contact and Cytoplasmic Projections | Restored Aerobic Respiration | [8] |
2 | BM-MSCs | Pulmonary Alveoli in mouse lungs | Connexin43 alveolar attachment and microvesicles | Protection against acute lung injury | [15] |
3 | BM-MSCs and iPSCs | Airway epithelial cells | Tunnel Tubes | Rescue cigarettesmoke induced damage | [20] |
4 | BM-MSCs | Bronchial Epithelial Cells | Tunnel Tubes and Miro1 | Rescue Bronchial Epithelial Injury | [21] |
5 | BM-MSCs | H9c2 cardiomyocyte cell line | Tunnel Tubes | Rescue cardiomyocytes in ischemia model | [22] |
6 | BM-MSCs | Cardiomyocytes | Tunnel Tubes | Repair damaged cardiomyocytes in failed myocardium | [23] |
7 | BM-MSCs | Cardiomyoblasts | Cell-Cell Connection and Tubular Connections | Rescue Cells from Ischemic Damage | [24] |
8 | BM-MSCs | Kidney Tubular Epithelial cells | Microvesicles | Recovery from acute kidney injury | [25] |
9 | BM-MSCs | Rat Cortical Neuronal Cells | Tunnel Tubes and Miro1 | Neuroprotective | [26] |
10 | BM-MSCs | Macrophages | Tunnel Tubes | Anti-Bacterial Activity | [27] |
11 | BM-MSCs | Macrophages | Extracellular Vesicles | Regulation of mitochondrial dynamics and Mitophagy | [28] |
12 | BM-MSCs | Acute myeloid leukemic cells | Cell-Cell Contact | Survival of Myeloid Cells | [18] |
13 | BM-MSCs | MDA-MB231 breast carcinoma cell line | Isolated mitochondria | Enhanced OXPHOS activity | [29] |
14 | iPSCs-MSCs | Corneal Epithelial Cells | Tunnel Tubes | Protection of corneal epithelial cells against alkali burn | [16] |
15 | AD- MSCs | Cardiomyocytes | Cell Fusion | Reprogram adult cardiac cells towards progenitor like state | [30] |
16 | WJ-MSCs | Cells devoid of mitochondria Osteosarcoma cells | Tunnel Tubes | Mitochondria function was rescued | [19] |