Fig. 4
From: Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration
Western Blot: Examples of Western blot protein expression are shown in (a). Levels of (b) ceramide synthase 2 (CerS2), (c) elongation of very long chain fatty acids 1 (ELOVL1), (d) inositol-requiring enzyme (IRE1) and (e) eukaryotic initiation factor 2 (eIF2α), (f) acetyl CoA carboxylase (ACC1) and (g) fatty acid synthase (FAS) protein expression (% of control) in the rat liver following acute administration of olanzapine (1 mg/kg), clozapine (12 mg/kg) or vehicle (control). Data presented as mean ± SEM, (n = 4–6/group). *p < 0.05 vs controls