From: Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration
 | Control | Olanzapine | Clozapine | ||||||
---|---|---|---|---|---|---|---|---|---|
Ceramide | |||||||||
 Total | 49.08 | ± | 1.19 | 33.96 | ± | 6.03 | 47.65 | ± | 2.81 |
 Cer 16:0 | 3.96 | ± | 0.72 | 2.05 | ± | 0.38 | 3.77 | ± | 1.02 |
 Cer 18:0 | 22.71 | ± | 1.84 | 18.75 | ± | 2.50 | 24.77 | ± | 0.91 |
 Cer 19:0 | 0.79 | ± | 0.03 | 0.60 | ± | 0.17 | 0.82 | ± | 0.07 |
 Cer 20:0 | 3.40 | ± | 0.11 | 2.93 | ± | 0.27 | 2.33 | ± | 0.33 |
 Cer 22:0 | 3.35 | ± | 0.40 | 3.28 | ± | 0.32 | 2.65 | ± | 0.28 |
 Cer 22:1 | 0.31 | ± | 0.15 | 0.20 | ± | 0.10 | 0.37 | ± | 0.14 |
 Cer 23:0 | 2.17 | ± | 0.29 | 2.14 | ± | 0.03 | 1.66 | ± | 0.23 |
 Cer 24:0 | 7.08 | ± | 0.97 | 6.71 | ± | 0.68 | 6.08 | ± | 0.93 |
 Cer 24:1 | 5.32 | ± | 0.40 | 3.46 | ± | 0.23 | 4.49 | ± | 0.70 |
 Cer 24:2 | 0.84 | ± | 0.10 | 0.44 | ± | 0.21 | 0.71 | ± | 0.17 |
 Cer 25:0 | 0.30 | ± | 0.14 | 0.31 | ± | 0.14 | 0.30 | ± | 0.15 |
Sphingomyelin | |||||||||
 Total | 521.23 | ± | 20.74 | 409.07 | ± | 69.83 | 472.09 | ± | 17.39 |
 SM 16:0 | 59.07 | ± | 12.48 | 51.95 | ± | 9.07 | 64.12 | ± | 8.68 |
 SM 17:0 | 5.98 | ± | 0.45 | 5.35 | ± | 0.23 | 5.91 | ± | 0.48 |
 SM 18:0 | 241.68 | ± | 10.63 | 213.19 | ± | 20.40 | 253.40 | ± | 9.12 |
 SM 18:1 | 11.29 | ± | 0.59 | 9.44 | ± | 1.29 | 10.44 | ± | 0.39 |
 SM 19:1 | 4.78 | ± | 0.18 | 4.57 | ± | 0.22 | 4.78 | ± | 0.18 |
 SM 20:0 | 25.45 | ± | 3.31 | 23.43 | ± | 2.63 | 15.27 | ± | 1.61 |
 SM 22:0 | 37.96 | ± | 5.27 | 43.44 | ± | 6.70 | 23.39 | ± | 2.75 |
 SM 22:1 | 4.51 | ± | 0.98 | 4.68 | ± | 1.09 | 2.68 | ± | 0.88 |
 SM 23:0 | 14.60 | ± | 1.48 | 18.36 | ± | 2.68 | 10.25 | ± | 1.09 |
 SM 24:0 | 42.86 | ± | 4.73 | 48.30 | ± | 7.24 | 29.11 | ± | 2.39 |
 SM 24:1 | 66.81 | ± | 8.28 | 49.84 | ± | 2.33 | 45.62 | ± | 4.91 |
 SM 24:2 | 8.69 | ± | 0.58 | 7.06 | ± | 0.25 | 7.12 | ± | 1.02 |