TY - JOUR AU - Wu, I-Chin AU - Liu, Wen-Chun AU - Chang, Ting-Tsung PY - 2018 DA - 2018/06/02 TI - Applications of next-generation sequencing analysis for the detection of hepatocellular carcinoma-associated hepatitis B virus mutations JO - Journal of Biomedical Science SP - 51 VL - 25 IS - 1 AB - Next-generation sequencing (NGS) is a powerful and high-throughput method for the detection of viral mutations. This article provides a brief overview about optimization of NGS analysis for hepatocellular carcinoma (HCC)-associated hepatitis B virus (HBV) mutations, and hepatocarcinogenesis of relevant mutations. SN - 1423-0127 UR - https://doi.org/10.1186/s12929-018-0442-4 DO - 10.1186/s12929-018-0442-4 ID - Wu2018 ER -