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Fig. 4 | Journal of Biomedical Science

Fig. 4

From: Applications of next-generation sequencing analysis for the detection of hepatocellular carcinoma-associated hepatitis B virus mutations

Fig. 4

The distribution of pathogenic frequencies in HCC-associated SNV I and SNV II. Almost all HCC-associated SNV I had pathogenic frequencies higher than 80% and the great majority of HCC-associated SNV II had either low (< 20%) or high (> 80%) pathogenic frequencies, i.e. a U-shaped distribution pattern. SNV I was defined as the dominant strain of HBV in non-HCC group. SNV II was defined as the variant other than SNV I at the same nucleotide position, i.e. the minor strain of HBV in non-HCC group

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