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Fig. 5 | Journal of Biomedical Science

Fig. 5

From: Applications of next-generation sequencing analysis for the detection of hepatocellular carcinoma-associated hepatitis B virus mutations

Fig. 5

The distribution of pathogenic frequencies in previously reported and novel HCC-associated SNVs. Among the 60 NGS-defined HCC-associated SNVs, 19 had been reported previously and 41 were novel ones. In 19 HCC-associated SNVs reported previously, 94.7% (18/19) had cut-off values of SNV frequency > 20%, expect nt456G, which had a cut-off value of 10.2%. In the other 41 novel HCC-associated SNVs, 68.3% (28/41) had cut-off values of SNV frequency > 20 and 31.7% (13/41) had cut-off values < 20%

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