Table 1 HCC-associated SNVs with their pathogenic frequencies through NGS analysis, categorized by level of supporting evidence

 53

C

4.5 (1.8, 11.5)

32

53

C

5.1 (1.6, 16.7)

52.4

 1896

A

3.5 (1.1,10.7)

96.5

1613

A

10.1 (1.2, 83.6)

86.7

 1899

A

5.8 (1.1, 31.0)

96.1

1653

T

4.2 (1.3, 14.2)

60.8

1674

C

11.5 (1.4, 94.8)

55.8

1753

G

3.1 (1.1, 9.4)

100

1764

A

4.6 (1.7, 12.4)

100

1846

T

3.1 (1.2, 8.2)

21.1

 1913

C

5.5 (1.1, 28.2)

94.3

1386

A

5.2 (1.1, 25.9)

96.7

 2441

C

11.5 (1.4, 96.5)

100

2875

A

5.6 (1.7, 18.3)

94.8

 2525

T

7.5 (1.5, 36.7)

95.5

3066

T

5.6 (1.2, 26.6)

86.8

3120

G

4.8 (1.6, 14.4)

95.9

 2444

C

4.8 (1.6, 14.3)

92.6

456

G

6.0 (1.2, 29.3)

10.2

 216

C

5.6 (1.2, 28.3)

100

293

G

2.9 (1.3, 6.4)

1.8

 273

G

5.0 (2.0, 12.8)

12.2

446

G

5.6 (2.0, 15.2)

6.4

 273

A

0.3 (0.1, 0.8)

55

633

A

5.6 (1.1, 27.5)

3.6

 529

G

4.1 (1.4, 12.0)

100

834

G

7.6 (2.1, 28.2)

76.9

 530

A

4.2 (1.3, 14.0)

100

1092

C

5.6 (1.2, 26.6)

50.1

 724

C

4.0 (1.3, 12.0)

91.7

1155

C

5.6 (1.2, 26.6)

87.1

 1173

G

9.2 (1.1, 76.5)

94.1

2201

T

3.7 (1.1, 11.9)

93.3

 1221

C

4.1 (1.1, 14.1)

4.3

2573

C

4.2 (1.3, 14.2)

100

 1242

G

5.1 (1.8, 14.6)

5.5

2594

A

4.0 (1.3, 12.4)

100

 1359

A

3.6 (1.0, 12.5)

2.4

2708

G

5.8 (1.5, 22.1)

100

 2095

G

3.2 (1.3, 8.0)

10.1

2840

T

8.3 (1.8, 38.3)

4.4

 2120

G

3.6 (1.0, 12.5)

67.2

2889

G

5.5 (1.8, 17.6)

85.3

 2213

G

9.8 (1.2, 83.1)

1.7

2901

T

4.1 (1.1, 15.4)

85.1

 2226

T

9.8 (1.2, 83.1)

1.7

2931

C

9.1 (2.0, 41.6)

87.1

 2227

G

9.8 (1.2, 83.1)

1.8

2988

C

9.0 (1.1, 73.6)

92.1

 2227

T

0.2 (0.1, 0.8)

95.5

2989

A

9.0 (1.1, 73.6)

91.7

 2583

G

6.5 (1.2, 32.3)

100

2997

T

9.0 (1.1, 73.6)

90.8

 2690

A

4.9 (1.2, 19.3)

12

2998

C

9.0 (1.1, 73.6)

92.2

3006

A

14.1 (1.8, 111.8)

94.2

3009

G

5.0 (1.0, 24.0)

92.9

3016

C

9.0 (1.1, 73.6)

92.9

3021

A

11.4 (1.4, 91.9)

92.6

3097

A

4.5 (1.2, 16.8)

93.5