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Table 3 Association between ApoE polymorphism, rs3810950 polymorphism and Alzheimer’s disease

From: CHAT gene polymorphism rs3810950 is associated with the risk of Alzheimer’s disease in the Czech population

ApoE/rs3810950 N Risk RR Odd OR (95% Cl) p
AD Controls
E3/E3 GG 182 157 0.54 1.16
E3/E3 GA 141 99 0.59 1.09 1.42 1.22 (0.87–1.7) 0.2354
E3/E3 AA 29 6 0.83 1.54 4.83 4.16 (1.68–10.28) 0.0010
E3/E4 GG 132 29 0.82 1.52 4.55 3.92 (2.49–6.18) < 0.0001
E3/E4 GA 118 47 0.72 1.33 2.51 2.16 (1.45–3.22) 0.0002
E3/E4 AA 23 7 0.77 1.43 3.29 2.84 (1.19–6.8) 0.0202
E4/E4 GG 16 6 0.73 1.35 2.67 2.3 (0.88–6.02) 0.1202
E4/E4 GA 10 2 0.83 1.54 5 4.31 (0.93–19.97) 0.0726
E4/E4 AA 7 1 0.88 1.63 7 6.03 (0.73–49.55) 0.0759
E2/E2 GG 3 1 0.75 1.39 3 2.59 (0.27–25.15) 0.6275
E2/E3 GG 26 29 0.47 0.87 0.9 0.78 (0.44–1.38) 0.3865
E2/E3 GA 16 23 0.41 0.76 0.7 0.6 (0.31–1.18) 0.1752
E2/E3 AA 9 5 0.64 1.19 1.8 1.55 (0.51–4.72) 0.5865
E2/E4 GG 20 6 0.77 1.43 3.33 2.87 (1.12–7.32) 0.0242
E2/E4 GA 13 4 0.76 1.41 3.25 2.8 (0.89–8.76) 0.0814
E1/E2 GG 2 1 0.67 1.24 2 1.72 (0.15–19.15) 1
E1/E4 GG 1 0 1 1.85 Inf Inf 1
  1. N number of subjects, OR odds ratio, CI confidence interval