Skip to main content

Advertisement

Fig. 3 | Journal of Biomedical Science

Fig. 3

From: Differential regulation of nimodipine-sensitive and -insensitive Ca2+ influx by the Na+/Ca2+ exchanger and mitochondria in the rat suprachiasmatic nucleus neurons

Fig. 3

CaV1.2 and CaV1.3 immunoreactivity and colocalization with NCX1. Distribution of immunoreactivity for CaV1.2 (a 1 ), CaV1.3 (b 1 ), and NCX1 (c 1 ) in the medial SCN. Scale bars: 100 μm. OC: optic chiasm. 3 V: third ventricle. The CaV1.2 immunoreactivity is present at or around the membrane (a 2 , a 3 ) and in the process (a 2 , marked by arrowheads), but not in the cytoplasm. Intense colocalization of CaV1.2 and NCX1 can be found at the cell membrane (c3) and in the process (c 2 ). The scale bar is 10 μm in a 2 and is the same in a 3 , c 2 , and c 3 . The CaV1.3 immunoreactivity also appears at or around the plasma membrane (b 2 –b 4 ) and in the cell process (b 4 , marked by arrowheads), and is particularly intense in the cytoplasm of cells located in the ventral region of the SCN (b 3 , b 4 ). Colocalization of CaV1.3 and NCX1 can be found in the cytoplasm of cells in the ventral region of the SCN (c4, c5) and in the cell process as discrete aggregates (c 5 , marked by arrowheads). The scale bar is 10 μm in b 2 and is the same in b 3 , b 4 , c 4 , and c 5 . Asterisks mark Hoechst-stained nuclei

Back to article page