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Fig. 6 | Journal of Biomedical Science

Fig. 6

From: Differential regulation of nimodipine-sensitive and -insensitive Ca2+ influx by the Na+/Ca2+ exchanger and mitochondria in the rat suprachiasmatic nucleus neurons

Fig. 6

FCCP effects on 20 K+-induced Ca2+ transients. a A representative experiment showing the averaged Ca2+ response (n = 11 cells) to 20 mM K+ for 20 s in control and in the presence of 0.1 μM FCCP. b Superimposition of Ca2+ transients evoked in control (trace a) and in the presence of FCCP for 5 (trace b), 25 (trace c), and 45 min (trace d). Note the larger amplitude and slower decay time course for Ca2+ transients in FCCP. c Superimposition of subtracted traces (b – a, c – a, and d – a) to indicate the FCCP-enhanced Ca2+ transients as time progressed. The control trace (a) was also superimposed for better comparison of their kinetics but truncated for better visualization of the plateau-like delay prior to the decay of the FCCP-enhanced Ca2+ transients

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