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Fig. 7 | Journal of Biomedical Science

Fig. 7

From: Differential regulation of nimodipine-sensitive and -insensitive Ca2+ influx by the Na+/Ca2+ exchanger and mitochondria in the rat suprachiasmatic nucleus neurons

Fig. 7

Preferential enhancement by FCCP of nimodipine-insensitive Ca2+ transients. a A representative experiment showing the effect of 2 μM nimodipine on 20 K+-induced Ca2+ response (an average of 12 cells) in the absence and then presence of 0.1 μM FCCP. Superimposition of Ca2+ transients to show the similar effect of FCCP on the Ca2+ transient evoked in the absence (b) and presence (c) of nimodipine. d Superimposition of subtracted traces (ab and cd) to show the minimal effect of FCCP on the nimodipine-sensitive Ca2+ transient. e Superimposition of subtracted traces to show that the FCCP-enhanced Ca2+ transients were similar in the absence (ca) and presence (db) of nimodipine, indicating that FCCP selectively enhanced nimodipine-insensitive Ca2+ rise

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