Table 1 Expression of ASICs in specific subsets of mechanoreceptors
From: Acid-sensing ion channels: dual function proteins for chemo-sensing and mechano-sensing
| Â | ASIC1 | ASIC1a | ASIC1b | ASIC2 | ASIC2a | ASIC2b | ASIC3 | ASIC4 |
|---|---|---|---|---|---|---|---|---|
Jugular nociceptor | SC-RT [125] | SC-RT [125] | SC-RT [125] | SC-RT [125] | Â | SC-RT [125] | SC-RT [125] | Â |
Nodose nociceptor | SC-RT [125] | Â | Â | SC-RT [125] | SC-RT [125] | Â | SC-RT [125] | SC-RT [125] |
Esophageal mechanoreceptor | SC-RT [125] | SC-RT [125] | SC-RT [125] | SC-RT [125] | SC-RT [125] | SC-RT [125] | SC-RT [125] | SC-RT [125] |
Muscle spindle | Â | Â | SC-RT [40] | IHC [126] | Â | SC-RT [40] | Â | |
Hair follicle: Lanceolate complex | Â | Â | Â | Â | Â | IHC [38] | Â | |
Hairy skin: Penicillate nerve | Â | Â | Â | IHC [32] | Â | Â | Â | Â |
Meissner’s corpscles |  |  |  | IHC [32] |  |  | IHC [38] |  |
Merkel cell/neurite complex | Â | Â | Â | IHC [32] | Â | Â | IHC [38] | Â |
Cutaneous nociceptor | Â | Â | Â | IHC [32] | Â | Â | IHC [38] | Â |
Baroreceptor | IHC [34] | Â | Â | IHC [34] | Â | Â | Â | |
Periodontal ligament Ruffini’s ending |  |  |  |  |  |  | IHC [36] |  |