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Table 1 Expression of ASICs in specific subsets of mechanoreceptors

From: Acid-sensing ion channels: dual function proteins for chemo-sensing and mechano-sensing

  ASIC1 ASIC1a ASIC1b ASIC2 ASIC2a ASIC2b ASIC3 ASIC4
Jugular nociceptor SC-RT [125] SC-RT [125] SC-RT [125] SC-RT [125]   SC-RT [125] SC-RT [125]  
Nodose nociceptor SC-RT [125]    SC-RT [125] SC-RT [125]   SC-RT [125] SC-RT [125]
Esophageal mechanoreceptor SC-RT [125] SC-RT [125] SC-RT [125] SC-RT [125] SC-RT [125] SC-RT [125] SC-RT [125] SC-RT [125]
Muscle spindle    SC-RT [40] IHC [126]   SC-RT [40] IHC [40] Reporter [40] SC-RT [40]  
Hair follicle: Lanceolate complex     IHC [30], IHC [32]    IHC [38]  
Hairy skin: Penicillate nerve     IHC [32]     
Meissner’s corpscles     IHC [32]    IHC [38]  
Merkel cell/neurite complex     IHC [32]    IHC [38]  
Cutaneous nociceptor     IHC [32]    IHC [38]  
Baroreceptor IHC [34]    IHC [34]    IHC [34] IHC [72]  
Periodontal ligament Ruffini’s ending        IHC [36]  
  1. IHC immunohistochemistry, SC-RT single cell RT-PCR