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Table 5 Hazard ratios for overall survival in the joint subgroups with platinum-based chemotherapy

From: Prognostic value of localization of epidermal growth factor receptor in lung adenocarcinoma

tEGFR/mutant

Number

Median (m)a

Unadjusted HR (95% CI)

p

Adjusted HRb (95%CI)

p

tEGFR mutant

11

18.2

1.0

 

1.0

 

tEGFR+ mutant

10

34.7

0.33 (0.12~ 0.92)

0.029

0.36 (0.13~ 1.02)

0.055

tEGFR mutant+

10

29.5

0.65 (0.41~ 1.04)

0.070

0.64 (0.39~ 1.05)

0.076

tEGFR+ mutant+

21

25.9

0.74 (0.56~ 0.97)

0.033

0.83 (0.59~ 1.15)

0.260

  1. Cox proportional model
  2. aMedian (m) = median survival time (month)
  3. bAdjusted hazard ratio with TKI
  4. Note: Boldfaces as statistical significance