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Table 4 Level of anthropometric parameters and hormones in different genotypes of rs4889 C/G in KISS1 gene in Saudi women with PCOS and Control groups

From: rs4889 polymorphism in KISS1 gene, its effect on polycystic ovary syndrome development and anthropometric and hormonal parameters in Saudi women

Variable

PCOS Group

(n = 28)

(Mean ± SD)

Control Group

(n = 30)

(Mean ± SD)

P-value

GG

n = 11

CG

n = 13

CC

n = 4

GG

n = 22

CG

n = 7

GG

CG

CC

Weight (Kg)

75.8 ± 11

74.1 ± 13

58.8 ± 4.1

57.5 ± 10

68.4 ± 9.6

0.0001**

0.362

0.157

Height (cm)

156. ± 6.8

156 ± 7.5

152 ± 5.91

162 ± 3.9

158.8 ± 3.5

0.007*

0.660

0.468

BMI (Kg/m2)

48.3 ± 6.7

47.2 ± 7.5

38 ± 1.76

35 ± 8

42.6 ± 6.43

0.0001**

0.219

0.157

FSH (IU/I)

6.52 ± 5.6

7.64 ± 5.8

4.9 ± 4.02

5.8 ± 2

5.5 ± 1.4

0.879

0.475

1.00

LH (IU/I)

13.7 ± 3.3

16.2 ± 3.8

15.3 ± 3.7

8.7 ± 1.2

8.6 ± 0.89

0.0001**

0.0001**

0.147

kisspeptin (pg\mL)

0.38 ± 0.2

0.43 ± 0.1

0.35 ± 0.18

0.37 ± .06

0.45 ± 0.06

0.349

0.968

1.00

  1. There was only 1 sample with a CC genotype in the control group, and was not used in the comparison
  2. *p-value< 0.05; **p-value< 0.001