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Table 4 Level of anthropometric parameters and hormones in different genotypes of rs4889 C/G in KISS1 gene in Saudi women with PCOS and Control groups

From: rs4889 polymorphism in KISS1 gene, its effect on polycystic ovary syndrome development and anthropometric and hormonal parameters in Saudi women

Variable PCOS Group
(n = 28)
(Mean ± SD)
Control Group
(n = 30)
(Mean ± SD)
P-value
GG
n = 11
CG
n = 13
CC
n = 4
GG
n = 22
CG
n = 7
GG CG CC
Weight (Kg) 75.8 ± 11 74.1 ± 13 58.8 ± 4.1 57.5 ± 10 68.4 ± 9.6 0.0001** 0.362 0.157
Height (cm) 156. ± 6.8 156 ± 7.5 152 ± 5.91 162 ± 3.9 158.8 ± 3.5 0.007* 0.660 0.468
BMI (Kg/m2) 48.3 ± 6.7 47.2 ± 7.5 38 ± 1.76 35 ± 8 42.6 ± 6.43 0.0001** 0.219 0.157
FSH (IU/I) 6.52 ± 5.6 7.64 ± 5.8 4.9 ± 4.02 5.8 ± 2 5.5 ± 1.4 0.879 0.475 1.00
LH (IU/I) 13.7 ± 3.3 16.2 ± 3.8 15.3 ± 3.7 8.7 ± 1.2 8.6 ± 0.89 0.0001** 0.0001** 0.147
kisspeptin (pg\mL) 0.38 ± 0.2 0.43 ± 0.1 0.35 ± 0.18 0.37 ± .06 0.45 ± 0.06 0.349 0.968 1.00
  1. There was only 1 sample with a CC genotype in the control group, and was not used in the comparison
  2. *p-value< 0.05; **p-value< 0.001