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Fig. 2 | Journal of Biomedical Science

Fig. 2

From: IL-33 receptor (ST2) deficiency downregulates myeloid precursors, inflammatory NK and dendritic cells in early phase of sepsis

Fig. 2

ST2 deficiency is associated with decreased number of myeloid precursors during early sepsis. a The frequencies and total number of splenic CD11b+Gr-1+ cells were analyzed by flow cytometry 12 h following CLP. b Representative plots show CD11b+Gr-1+ cells in septic ST2−/− and WT mice. c The percentage and total number of splenic CD11b+Ly6G+Ly6Clow granulocytic myeloid precursors. d The percentage and total number of splenic CD11b+Ly6GLy6Chigh monocytic myeloid precursors. e Representative plots denote the frequencies of granulocytic and monocytic myeloid precursors in spleen of septic ST2−/− and WT mice. Data are presented as mean ± SE, n = 4–7 mice per group. *p < 0.05, **p < 0.01

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