Skip to main content

Table 1 Baseline patient characteristics

From: The human C-type lectin 18 is a potential biomarker in patients with chronic hepatitis B virus infection

Variables Total HBeAg-negative HBeAg-positive P Value
Mean ± SD or N (%) (n = 271) (n = 170) (n = 101)  
Age 47.39 ± 11.35 51.57 ± 10.45 40.37 ± 10.44 <  0.0001T
Gender 0.6454C
 Man 187 (69.0) 119 (70.0) 68 (67.33)  
 Woman 84 (31.0) 51 (30.0) 33 (32.67)
Genotype 0.0003C
 B 166 (62.88) 118 (71.08) 48 (48.98)  
 C 98 (37.12) 48 (28.92) 50 (51.02)
HBsAg: log10 IU/mL 3.34 ± 0.84 3.04 ± 0.89 3.85 ± 0.66 <  0.0001T
HBV DNA: log10 IU/mL 6.89 ± 2.16 5.91 ± 1.84 8.56 ± 0.93 <  0.0001T
Cirrhosis 0.0028C
 No 182 (67.16) 103 (60.59) 79 (78.22)  
 Yes 89 (32.84) 67 (39.41) 22 (21.78)
Fatty liver 0.2510C
 No 133 (49.08) 88 (51.76) 45 (44.55)  
 Yes 138 (50.92) 82 (48.42) 56 (55.45)
Albumin: g/dL 4.07 ± 0.51 4.04 ± 0.54 4.10 ± 0.48 0.5446T
ALT: IU/L 281.5 ± 411.2 210.8 ± 333.2 400.5 ± 472.3 0.0002T
Total bilirubin: mg/dL 1.40 ± 1.34 1.32 ± 0.95 1.54 ± 1.54 0.7096T
Platelet: × 103/μL 161.0 ± 60.73 149.4 ± 65.8 180.8 ± 58.1 0.0004T
PT: seconds prolonged 1.71 ± 2.00 1.69 ± 1.73 1.86 ± 1.91 0.3551T
Cr: mg/dL 0.88 ± 0.49 0.90 ± 0.61 0.86 ± 0.40 0.2857T
AFP: ng/mL 25.31 ± 75.62 21.24 ± 44.57 32.17 ± 89.88 0.4094T
Numbers of liver biopsy 164 105 59  
 METAVIR Activity grade 0.5302C
  0,1 97 (59.15) 64 (60.95) 33 (55.93)  
  2,3 67 (40.85) 41 (39.05) 26 (44.07)
 METAVIR Fibrosis stage 0.0949C
  0–2 91 (57.59) 52 (52.53) 39 (66.10)  
  3,4 67 (42.41) 47 (47.47) 20 (33.90)
  1. T Student’s T-test, C Chi-squared test