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Table 2 Correlation between Axl or TNS2, and various markers using pancreatic tissue arrays

From: AXL phosphorylates and up-regulates TNS2 and its implications in IRS-1-associated metabolism in cancer cells

 

r

p

Tensin2

 Glut4

0.537

0.001*

 IRS-1

0.335

0.043*

 Ki-67

0.432

0.012*

 CD31

0.435

0.011*

 E-cadherin

0.289

0.102

 N-cadherin

0.452

0.008*

 Fibronectin

- 0.361

0.039*

 Caspase3

- 0.083

0.644

 pAkt (nuclei)

0.297

0.093

 pAkt (cytoplasm)

- 0.029

0.872

 pErk (nuclei)

0.182

0.319

 pErk (cytoplasm)

0.229

0.200

Axl

 Glut4

0.247

0.165

 IRS-1

0.133

0.461

 Ki-67

0.119

0.509

 CD31

0.251

0.159

 E-cadherin

0.072

0.690

 N-cadherin

- 0.168

0.350

 Fibronectin

- 0.345

0.049*

 Caspase3

0.149

0.408

 pAkt (nuclei)

0.058

0.746

 pAkt (cytoplasm)

0.217

0.224

 pErk (nuclei)

0.186

0.307

 pErk (cytoplasm)

0.033

0.856

  1. The correlations were evaluated using the Pearson correlation test
  2. Glut4 and IRS1 are involved in glycolysis; Ki-67, proliferation marker; CD31, angiogenesis marker; E-cadherin, epithelial marker; N-cadherin and fibronectin, mesenchymal marker; Caspase 3, apoptosis marker. Patient number = 33, *p < 0.05