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Table 2 Sexual behavioral and reproductive characteristics of HPV positive patients and controls

From: Genetic variant in CXCL12 gene raises susceptibility to HPV infection and squamous intraepithelial lesions development: a case-control study

Variable

HPV non-infected

HPV infected

p value*

OR

CI95%

p value

n

(%)

n

(%)

Contraceptive method

    

0.216

   

 No

114

(59.70)

83

(54.20)

 

1.00

Reference

 

 Yes, hormonal

63

(33.00)

52

(34.00)

 

1.134

0.713–1.802

0.569

 Yes, condom

13

(6.80)

13

(8.50)

 

1373

0.605–3.116

0.448

 Yes, both

1

(0.50)

5

(3.30)

 

6.867

0.788–59.882

0.081

Number of pregnancies

    

0.017

   

 0

15

(7.70)

26

(16.30)

 

1.00

Reference

 

 1

33

(17.00)

42

(26.30)

 

0.451

0.243–0.835

0.011

 2

61

(31.50)

35

(21.90)

 

0.540

0.286–1.020

0.058

 3

48

(24.50)

33

(20.60)

 

0.499

0.193–1.043

0.063

 4

21

(10.80)

12

(7.50)

 

0.589

0.245–1.146

0.237

 ≥ 5

16

(8.50)

12

(7.40)

 

1.362

0.623–2.977

0.439

Abortion

    

0.092

   

 No

137

(78.28)

107

(80.45)

 

1.00

Reference

 

 Yes

38

(21.72)

26

(19.55)

 

0.876

0.501–1.533

0.643

Age at first sexual intercourse (years)

    

0.265

   

 ≤17

102

(53.70)

89

(59.70)

 

1.00

Reference

 

 ≥18

88

(46.30)

60

(40.30)

 

0.782

0.506–1.206

0.266

Age at menarche (years)

    

0.379

   

 ≤12

89

(53,65)

82

(54,67)

 

1.00

Reference

 

 ≥13

103

(46,35)

68

(45,33)

 

0.717

0.467–1.101

0.128

Sexual partners during the lifetime

    

0.007

   

 1

76

(40.60)

31

(23.80)

 

1.00

Reference

 

 2–3

53

(28.40)

44

(33.80)

 

2.035

1.142–3.628

0.016

 ≥4

58

(31.00)

55

(42.40)

 

2.325

1.332–4.059

0.003

Sexual partners within the past 6 months

    

0.529

   

 0

26

(13.90)

24

(18.20)

 

1.00

Reference

 

 1

158

(84.50)

103

(78.00)

 

0.706

0.385–1.297

0.262

 ≥2

3

(1.60)

5

(3.80)

 

1.806

0.389–8.382

0.451

  1. *Analysis by two-sided Chi-square (Χ2) test and p < 0.05 as significance level (SPSS Inc., Chicago, Illinois, USA). Some categories did not complete the total of patients due to lack of data. Significant p values are presented in bold