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Table 2 Sexual behavioral and reproductive characteristics of HPV positive patients and controls

From: Genetic variant in CXCL12 gene raises susceptibility to HPV infection and squamous intraepithelial lesions development: a case-control study

Variable HPV non-infected HPV infected p value* OR CI95% p value
n (%) n (%)
Contraceptive method      0.216    
 No 114 (59.70) 83 (54.20)   1.00 Reference  
 Yes, hormonal 63 (33.00) 52 (34.00)   1.134 0.713–1.802 0.569
 Yes, condom 13 (6.80) 13 (8.50)   1373 0.605–3.116 0.448
 Yes, both 1 (0.50) 5 (3.30)   6.867 0.788–59.882 0.081
Number of pregnancies      0.017    
 0 15 (7.70) 26 (16.30)   1.00 Reference  
 1 33 (17.00) 42 (26.30)   0.451 0.243–0.835 0.011
 2 61 (31.50) 35 (21.90)   0.540 0.286–1.020 0.058
 3 48 (24.50) 33 (20.60)   0.499 0.193–1.043 0.063
 4 21 (10.80) 12 (7.50)   0.589 0.245–1.146 0.237
 ≥ 5 16 (8.50) 12 (7.40)   1.362 0.623–2.977 0.439
Abortion      0.092    
 No 137 (78.28) 107 (80.45)   1.00 Reference  
 Yes 38 (21.72) 26 (19.55)   0.876 0.501–1.533 0.643
Age at first sexual intercourse (years)      0.265    
 ≤17 102 (53.70) 89 (59.70)   1.00 Reference  
 ≥18 88 (46.30) 60 (40.30)   0.782 0.506–1.206 0.266
Age at menarche (years)      0.379    
 ≤12 89 (53,65) 82 (54,67)   1.00 Reference  
 ≥13 103 (46,35) 68 (45,33)   0.717 0.467–1.101 0.128
Sexual partners during the lifetime      0.007    
 1 76 (40.60) 31 (23.80)   1.00 Reference  
 2–3 53 (28.40) 44 (33.80)   2.035 1.142–3.628 0.016
 ≥4 58 (31.00) 55 (42.40)   2.325 1.332–4.059 0.003
Sexual partners within the past 6 months      0.529    
 0 26 (13.90) 24 (18.20)   1.00 Reference  
 1 158 (84.50) 103 (78.00)   0.706 0.385–1.297 0.262
 ≥2 3 (1.60) 5 (3.80)   1.806 0.389–8.382 0.451
  1. *Analysis by two-sided Chi-square (Χ2) test and p < 0.05 as significance level (SPSS Inc., Chicago, Illinois, USA). Some categories did not complete the total of patients due to lack of data. Significant p values are presented in bold