| | Model 1 | Model 2 | Model 3 | Model 4 | Model 5 | Model 6 | Model 7 |
|---|
GG |
OR | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
CI95% | Reference | Reference | Reference | Reference | Reference | Reference | Reference |
p value | | | | | | | |
Allele A carrier |
OR |
4.004
|
4.416
|
4.878
|
4.836
|
4.824
|
4.887
|
4.947
|
CI95% | (2.472–6.483) | (2.677–7.284) | (2.865–8.308) | (2.819–8.296) | (2.811–8.279) | (2.829–8.442) | (2.854–8.575) |
p value |
< 0.001
|
< 0.001
|
< 0.001
|
< 0.001
|
< 0.001
|
< 0.001
|
< 0.001
|
- Logistic regression analysis with HPV as dependent variable (reference group = non-infected women) and CXCL12 rs1801157 polymorphism as explanatory variable, adjusted for several con- founders according to the proposed models (p < 0.05 as significance level). (SPSS Inc., Chicago, Illinois, USA). Significant p values are presented in bold
- Model 1: CXCL12 polymorphism adjusted for knowledge about HPV;
- Model 2: CXCL12 polymorphism adjusted for knowledge about HPV and age;
- Model 3: CXCL12 polymorphism adjusted for knowledge about HPV, age and monthly income;
- Model 4: CXCL12 polymorphism adjusted for knowledge about HPV, age, monthly income and smoking status;
- Model 5: CXCL12 polymorphism adjusted for knowledge about HPV, age, monthly income, smoking status and number of pregnancies;
- Model 6: CXCL12 polymorphism adjusted for knowledge about HPV, age, monthly income, smoking status, number of pregnancies, and number of sexual partners;
- Model 7: CXCL12 polymorphism adjusted for knowledge about HPV, age, monthly income, smoking status, number of pregnancies, number of sexual partners and marital status
