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Table 2 Effects of prebiotics and probiotics in clinical studies

From: Visceral pain: gut microbiota, a new hope?

Participants

Treatment

Length of Trial

Outcomes

References

50 IBS children, Rome II criteria.

Lactobacillus GG vs placebo.

6 weeks

LGG ↓ incidence abdominal distention.

[50]

48 IBS patients, Rome II criteria.

VSL#3 vs placebo.

4 and 8 weeks

↓ flatulence and colonic transit.

[39]

30 Rome III FC patients; 30 controls.

VSL#3 vs placebo.

2 weeks

VSL#3 ↑complete spontaneous bowel movements.

[40]

59 IBS children.

VSL#3 vs placebo.

6 weeks

VSL#3 ↓ abdominal pain/discomfort, and bloating/gassiness.

[33]

104 children diagnosed with FAPD, IBS or FD.

Lactobacillus GG vs placebo.

4 weeks.

LGG treatment moderately improved abdominal pain.

[30]

105 FBD patients.

sc-FOS vs placebo.

6 weeks

sc-FOS ↓ intensity of digestive disorder symptoms ↑ quality of life, ↑ discomfort scores.

[56]

  1. Abbreviations: FBD Functional Bowel Disorders, FAPD Functional Abdominal Pain Disorders, FD Functional Dyspepsia, sc-FOS short-chain Fructo-oligosaccharides