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Fig. 4 | Journal of Biomedical Science

Fig. 4

From: Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology

Fig. 4

Znf179 interacts with TDP-43. a and b 293 T cells transiently transfected with Flag-mZnf179 (a) or N2a cells stably expressing GFP-mZnf179 (b) were immunoprecipitated with anti-TDP-43 or anti-Znf179 antibodies and immunoblotted with ant-TDP-43 and anti-Znf179 antibodies. c and d The total brain lysates of wild-type or Znf179-knockout mice were immunoprecipitated with either anti-TDP-43 or anti-Znf179 antibodies and immunoblotted with both anti-Znf179 and anti-TDP-43 antibodies

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