Fig. 6
From: A new approach to study the sex differences in adipose tissue
Schematic of differentiation of surface-tethered spheroids of hASCs atop a surface coated with elastin-like polypeptide-polyethyleneimine (ELP-PEI). The PEI repels the cells from the coated surface and induces spheroid formation, while the biocompatible ELP encourages the formed spheroids to adhere to the surface. Such surface-tethered spheroids can then be differentiated to the desired lineage (e.g., adipogenic lineage) by their differentiation and maturation under a suitable, physiologically-relevant microenvironment. (Reprinted with permission from [74])