Table 1 Main characteristics of white, brown, and beige adipocytes
From: A new approach to study the sex differences in adipose tissue
| Â | WHITE ADIPOSE TISSUE | Beige adipose tissue | brown adipose tissue |
|---|---|---|---|
origin | - Myf5-negative cells | - Myf5-negative cells - White adipose tissue - Sca-1+ progenitor cells - Smooth muscle cells progenitors - PDGFRα+ cells | - Mainly Myf5-positive cells |
LIPID DROPLET | Unilocular | Multilocular | Multilocular |
NUCLEUS | Periferic | Middle | Middle |
MITOCHONDRIA | Low | Low to High | High |
function | Lipid/Energy storage | Thermogenesis (dependent on the stimuli) | Thermogenesis and Autocrine, Paracrine, Endocrine roles |
human localization | Subcutaneous, intraabdominal | Cervical, parasternal, supraclavicular, para- and prevertebral | Interscapulum, supraclavicular, cervical, parasternal, para- and prevertebral, omental, axillary, kidneys |
rodents localization | Inguinal subcutaneous, epididymal, Intraabdominal, epicardium | Subcutaneous axillar and inguinal, epicardium | Interscapulum, perivascular |
cardiovascular disease | Positive related | Negative related | Negative related |