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Table 1 Serum anti-inflammatory cytokine Levels and CRP (ng/ml) amongst HIV infected subjects before commencement of HAART, 6 months into HAART and 1 year into HAART (±SD)

From: The effects of highly active antiretroviral therapy on the serum levels of pro-inflammatory and anti-inflammatory cytokines in HIV infected subjects

Group

IL-4 (Pg/ml)

IL-10 (Pg/ml),

TGF-β (Pg/ml),

Before commencement of HAART {a} (n = 50)

26.67 ± 4.39

31.57 ± 6.35

102.77 ± 30.53

6 Months into HAART{b} (n = 50)

7.98 ± 6.93

18.47 ± 5.29

85.03 ± 28.33

1 Year into HAART{c} (n = 50)

4.42 ± 2.11

7.05 ± 2.43

61.24 ± 22.08

Control {d} (n = 50)

3.68 ± 1.59

4.66 ± 2.12

39.20 ± 14.39

F Value

15.93

30.47

99.70

P Value

0.02

0.00

0.00

{a} Vs {b}

P < 0.05

P < 0.05

P < 0.05

{a} Vs {c}

P < 0.05

P < 0.05

P < 0.05

{a} Vs {d}

P < 0.05

P < 0.05

P < 0.05

{b} Vs {c}

P < 0.05

P < 0.05

P < 0.05

{b} Vs {d}

P < 0.05

P < 0.05

P < 0.05

{c} Vs {d}

P > 0.05

P > 0.05

P < 0.05

  1. IL-4 Interleukin 4, IL-10 Interleukin 10, TGF-β Tissue Growth Factor Beta, HAART Highly Active Antiretroviral Therapy, Vs Versus