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Table 2 Serum pro-inflammatory cytokine Levels amongst HIV infected subjects before commencement of HAART, 6 months into HAART and 1 year into HAART (±SD)

From: The effects of highly active antiretroviral therapy on the serum levels of pro-inflammatory and anti-inflammatory cytokines in HIV infected subjects

Group

IL-6 (Pg/ml)

INF-γ (Pg/ml)

TNF-α (Pg/ml)

Before commencement of HAART {a} (n = 50)

18.34 ± 5.83

0.78 ± 0.06

41.32 ± 12.99

6 Months into HAART{b} (n = 50)

10.43 ± 4.98

2.25 ± 0.91

29.32 ± 10.51

1 Year into HAART{c} (n = 50)

7.05 ± 3.43

2.64 ± 0.96

15.98 ± 4.81

Control {d} (n = 50)

4.62 ± 1.04

4.89 ± 0.23

9.40 ± 3.52

F Value

60.90

11.37

75.62

P Value

0.00

0.02

0.00

{a} Vs {b}

P < 0.05

P < 0.05

P < 0.05

{a} Vs {c}

P < 0.05

P < 0.05

P < 0.05

{a} Vs {d}

P < 0.05

P < 0.05

P < 0.05

{b} Vs {c}

P < 0.05

P < 0.05

P < 0.05

{b} Vs {d}

P > 0.05

P < 0.05

P < 0.05

{c} Vs {d}

P > 0.05

P < 0.05

P < 0.05

  1. IL-6 Interleukin 6, INF-γ Interferon Gamma, TNF-α Tumour Necrosis Factor alpha, Vs Versus, HAART Highly Active Antiretroviral Therapy, n number of participants