The effects of highly active antiretroviral therapy on the serum levels of pro-inflammatory and anti-inflammatory cytokines in HIV infected subjects

Table 4 Correlation between viral load (Log₁₀ copies/ml), CD4 + T cells (/μl), and interleukins in HIV infected subjects before commencement of HAART

parameters	n	r	P value
Viral load Vs IL-4	50	0.34	< 0.05
Viral Load Vs IL-6	50	0.62	< 0.05
Viral Load Vs IL-10	50	0.02	> 0.05
Viral Load Vs INF-γ	50	−0.43	< 0.05
Viral Load Vs TNF-α	50	0.44	< 0.05
Viral Load Vs TGF-β	50	0.57	< 0.05
Viral load and CD4+ T cells	50	0.72	< 0.01
CD4+ T cells and IL-4	50	−0.34	< 0.05
CD4+ T cells and INF-γ	50	0.42	< 0.05
CD4+ T cells and TNF-α	50	−0.42	< 0.05
CD4+ T cells and TGF-β	0	−0.66	< 0.01

Correlation was analyzed by Pearson’s correlation
Vs Versus Vs, HAART Highly Active Antiretroviral Therapy, n number of participants, IL-4 Interleukin 4, IL-10 Interleukin 10, TGF-β Tissue Growth Factor Beta
IL-6 Interleukin 6, INF-γ Interferon Gamma, TNF-α Tumour Necrosis Factor alpha

ISSN: 1423-0127